What is U-BRITE?

U-BRITE (UAB Biomedical Research Information Technology Enhancement) assembles new and existing HIPAA-compliant, high-performance informatics tools to provide researchers with a means to better manage and analyze clinical and genomic data sets and implements a “translational research commons” to facilitate and enable interdisciplinary team science across geographical locations.

  • Access to clinical data from Clinical Data Repository to build cohorts 
  • Access to genomic and other omics data from Omics Data Repository to perform detailed analytical characterizations
  • Provides self-service analysis to biologists via Jupyter Notebooks and other Analysis Gateway abstractions
  • Encourages participation in Jupyter Notebook, git, conda, and Docker ecosystems, which facilitate more reproducible research and team science
  • Brings clinical researchers in closer contact with data scientists, informatics architects, and computer programmers
  • Enables quick prototyping for new methods and tools
  • Enables sharing of complex data to bioinformaticians

About Us


James Cimino, MD, FACMI, FACP

Director, UAB Informatics Institute
Professor of Medicine

Steering Committee

Robert Kimberly, MD

Director, UAB Center for Clinical Translational Science
Senior Associate Dean for Clinical and Translational Research
Associate Vice President for Medicine and Biomedical Research

Ralph Zottola, PhD

Assistant Vice President for Researching Computing
Chief Architect for UAB Research Computing Applications

Bruce Korf, MD, PhD

Chief Genomics Officer
UAB Medicine Co-Director, UAB-HudsonAlpha Center for Genomic Medicine
Associate Director for Rare Diseases, Hugh Kaul Personalized Medicine Institute

Program Director

Jake Y. Chen, PhD

Professor of Genetics, Computer Science and Biomedical Engineering
Chief Bioinformatics Officer
Associate Institute Director, UAB Informatics Institute

Informatics Team

John Osborne,​ PhD

Project Design and Liaison
Assistant Professor of Medicine
UAB Informatics Institute

Wayne Liang​, MD

Data Governance
Assistant Professor of Pediatrics
UAB Informatics Institute

Matthew Wyatt​

Clinical Data Access
Director of Clinical Research Informatics
UAB Informatics Institute

Amy Wang, MD, MBI

Associate Professor of Medicine and Family and Community Medicine
UAB Informatics Institute

Zhandos Sembay

Architecture, Design, and Tech Support
UAB Informatics Institute

Web Team

Nafisa Ajala

Informatics Program Specialist
UAB Informatics Institute