“HomoloGene is a system that automatically detects homologs, including paralogs and orthologs, among the genes of 21 completely sequenced eukaryotic genomes. HomoloGene reports include homology and phenotype information drawn from Online Mendelian Inheritance in Man (27), Mouse Genome Informatics (28), Zebrafish Information Network (29), Saccharomyces Genome Database (30) and FlyBase (31). Information about the HomoloGene build procedure is provided at www.ncbi.nlm.nih.gov/HomoloGene/HTML/homologene_buildproc.html.”

Excerpted from paper at doi: 10.1093/nar/gkt1146.

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HomoloGene is an automated system for constructing putative homology groups from the complete gene sets of a wide range of eukaryotic species hosted by the National Center for Biotechnology Information (NCBI) and funded by intramural National Institutes of Health (NIH) funding.

The data used for the analyses described in this manuscript were obtained from the NCBI FTP server and staged to dedicated shared storage at UAB in order to better facilitate researcher access to important public data. These locally hosted data are documented and supported by the Informatics Institute‘s U-BRITE team and infrastructure.